Thiamin and oxidative stress
نویسندگان
چکیده
word count: 195
منابع مشابه
Thiamin confers enhanced tolerance to oxidative stress in Arabidopsis.
Thiamin and thiamin pyrophosphate (TPP) are well known for their important roles in human nutrition and enzyme catalysis. In this work, we present new evidence for an additional role of these compounds in the protection of cells against oxidative damage. Arabidopsis (Arabidopsis thaliana) plants subjected to abiotic stress conditions, such as high light, cold, osmotic, salinity, and oxidative t...
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Thiamin plays a key role in the maintenance of brain function. Thiamin diphosphate is cofactor for several enzymes involved in glucose metabolism whereas thiamin triphosphate has distinct properties at the neuronal membrane. Thiamin metabolism in the brain is compartmented between neurons and neighbouring glial cells. Thiamin deficiency is commonly encountered in severe malnutrition associated ...
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Thiamin (vitamin B1), a member of the water-soluble family of vitamins, is essential for normal cellular functions; its deficiency results in oxidative stress and mitochondrial dysfunction. Pancreatic acinar cells (PAC) obtain thiamin from the circulation using a specific carrier-mediated process mediated by both thiamin transporters -1 and -2 (THTR-1 and THTR-2; encoded by the SLC19A2 and SLC1...
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There has been much research into autism or autistic spectrum disorder (ASD) and room for considerable conjecture regarding the etiology of these disorders remain. ASD is marked by a complex interaction between environmental factors and genetic predisposition, including epistasis. This manuscript argues that changes in oxidative metabolism, thiamine homeostasis, heavy metal deposition and cellu...
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THIAMIN IS A WATER-SOLUBLE B1 vitamin that regulates critical cellular processes, such as oxidative energy metabolism, adenosine triphosphate (ATP) production, and mitochondrial function; thus, it is referred to as the energy vitamin (3, 5). Based on these known roles of thiamin, deficiency of this vitamin can lead to serious cellular impairments, including reduced cellular energy, increased ox...
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